GWAS-related meQTLs across different cancer types

We identified 2,214,458 meQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).



e.g., "BLCA"
e.g., "rs10000012"
e.g., "CTBP1"
e.g., "cg02980000"
Cancer type
QTL type
tagSNP
LD
SNP ID
SNP position (hg19)
alleles
probe
Gene position (hg19)
Gene
Beta
t-stat
r
p-value
Traits
BLCA trans rs11997175 0.846 rs11776207 chr8:33765126 G/T cg23671719 chr19:2841288 ZNF555 -0.4 -6.34 -0.31 6.54E-10 Body mass index;
BLCA trans rs11098499 0.954 rs12508504 chr4:120410607 A/C cg25214090 chr10:38739885 LOC399744 0.49 8.04 0.38 1.16E-14 Corneal astigmatism;
BLCA trans rs853679 0.556 rs13197633 chr6:28174757 G/A cg01620082 chr3:125678407 NA -0.97 -9.07 -0.42 6.29E-18 Depression;
BLCA trans rs1908814 0.516 rs13275143 chr8:11796990 T/A cg08975724 chr8:8085496 FLJ10661 0.44 6.87 0.33 2.6E-11 Neuroticism;
BLCA trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg03929089 chr4:120376271 NA -0.82 -15.6 -0.62 9.61E-43 Height;
BLCA trans rs60843830 0.596 rs17041320 chr2:112051 A/G cg11347411 chr7:150020925 ACTR3C;LRRC61 0.39 6.09 0.3 2.73E-9 Spherical equivalent (joint analysis main effects and education interaction);
BLCA trans rs564343 0.583 rs2430978 chr11:65816656 G/C cg26701943 chr11:108369231 KDELC2 -0.46 -7.24 -0.35 2.58E-12 Obesity (early onset extreme);
BLCA trans rs2726453 0.646 rs2726502 chr4:106298896 A/G cg26720404 chr5:143584869 KCTD16 0.37 6.02 0.3 4.03E-9 Intelligence (multi-trait analysis);
BLCA trans rs853679 0.607 rs34218844 chr6:28290647 T/C cg01620082 chr3:125678407 NA -0.91 -8.93 -0.42 1.83E-17 Depression;
BLCA trans rs9291683 0.679 rs3756225 chr4:10094133 G/C cg26043149 chr18:55253948 FECH -0.51 -7.76 -0.37 7.94E-14 Bone mineral density;
BLCA trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg03759077 chr2:153575599 ARL6IP6 0.4 6.3 0.31 8.33E-10 Alopecia areata;
BLCA trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg13456812 chr6:167369504 RNASET2 0.39 6.12 0.3 2.32E-9 Alopecia areata;
BLCA trans rs7299099 0.966 rs3858607 chr12:94536803 C/G cg17158761 chr14:21077876 NA 0.41 6.52 0.32 2.18E-10 Alopecia areata;
BLCA trans rs61931739 0.534 rs4365131 chr12:34053308 T/C cg13010199 chr12:38710504 ALG10B 0.49 7.93 0.38 2.48E-14 Morning vs. evening chronotype;
BLCA trans rs10510628 0.739 rs4396848 chr3:29848020 C/G cg09101826 chr15:90294471 MESP1 0.41 6.02 0.3 4.05E-9 Bone mineral density;